个人简介：

张媛媛，女，1993年2月生，山西运城人，博士，中共党员，现任山西农业大学生命科学学院讲师。

邮箱:zhangyyuan0221@sxau.edu.cn

教育背景：

2011.09-2015.06，山西农业大学，植物保护，学士

2015.09-2020.06，中国农业大学，化学，硕博

研究方向：

荧光探针用于重金属离子、活性氧、酶、核酸等的检测、细胞定位及生物成像研究，载药型荧光探针构建

发表论文：

1. Zhang Y, Chen X, Liu X, et al. A highly sensitive multifunctional sensor based on phenylene-acetylene for colorimetric detection of Fe²⁺ and ratiometric fluorescent detection of Cd²⁺ and Zn²⁺. Sens. Actuators, B., 2018, 273, 1077-1084.

2. Zhang Y, Chen X, Liu X, et al. A highly selective and ultrafast near-infrared fluorescent turn-on and colorimetric probe for hypochlorite in living cells. Anal. Chim. Acta., 2019, 1078, 135-141.

3. Zhang Y, Chen X, Liu J, et al. A highly selective and sensitive fluorescent chemosensor for distinguishing cadmium (II) from zinc (II) based on amide tautomerization. New J. Chem., 2018, 42, 19245-19251.

4. Zhang Y, Ma Y, Wang Z, et al. A novel colorimetric and far-red emission ratiometric fluorescent probe for the highly selective and ultrafast detection of hypochlorite in water and its application in bioimaging. Analyst., 2020,145, 939-945.

5. Chen X, Ma X, Zhang Y, et al. Ratiometric fluorescent probes with a self-immolative spacer for real-time detection of β-galactosidase and imaging in living cells. Anal. Chim. Acta., 2018, 1033, 193-198.

6. Liu J, Chen X, Zhang Y, et al. A novel 3-hydroxychromone fluorescent probe for hydrogen sulfide based on an excited-state intramolecular proton transfer mechanism. New J. Chem., 2018, 42, 12918-12923.

7. Liu J, Chen X, Zhang Y, et al. A novel xanthene-based colorimetric and fluorescence probe for detection of H2S in living cells. J. Lumin., 2018, 204, 480-484.

8. Zhang X, Chen X, Zhang Y, et al. A high-sensitivity fluorescent probe with a selfimmolative spacer for real-time radiometric detection and imaging of alkaline phosphatase activity. New J. Chem., 2019, 43, 11887-11892.

9. Chen X, Zhang X, Ma X, Zhang Y, et al. Novel fluorescent probe for rapid and ratiometric detection of β-galactosidase and live cell imaging. Talanta., 2019, 192, 308-313.

10. Chen X, Wang H, Ma X, Wang M, Zhang Y, et al. Colorimetric and fluorescent probe for real-time detection of palladium (II) ion in aqueous medium and live cell imaging. Dyes Pigm., 2018, 148, 286-291.

11. Zhang X, Chen X, Liu K, Zhang Y, et al. Near-infrared ratiometric probe with a self-immolative spacer for rapid and sensitive detection of alkaline phosphatase activity and imaging in vivo. DOI: 10.1016/j.aca.2019.10.001.

12. Chen X, Ma X, Wang H, Wang M, Zhang Y, et al. A coumarin-based colorimetric and fluorescent dual probe for palladium (II) ions that can be used in live cells. New J. Chem., 2017, 41, 8026-8030.

参与科研项目：

1. 国家“十二五”科研用试剂产业链创新体系构建项目，2015BAK45B01.

2. 国家重点研发计划“京津冀设施农业面源和重金属污染防控技术示范”项目，2016YFD0801006.

专利：

1. 发明专利：郑冰，高贵，陈相助，张媛媛，侯士聪，王敏. 一种阿莫曲坦的合成方法，ZL 201511022378.2

2. 发明专利：侯士聪，高贵，陈相助，刘晶晶，张媛媛，张雪焱. 5-氨基吡唑类化合物在调节植物生长方面的应用，ZL201711326981.9